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Cold email

An AI appointment setter for cold email, replying from the same mailbox.

The short answer

An AI appointment setter for cold email reads every reply to your campaigns and turns interested ones into meetings. Underfive connects to Smartlead, Instantly, Email Bison, PlusVibe, Lemlist, Gmail and Outlook, answers in under 5 minutes from the mailbox the prospect replied to, proposes real times and books the call.

50 free credits · no credit card · updated October 2026

Cold email replies are messy: auto-replies, referrals, "who are you?", "send pricing". Sorting them across dozens of mailboxes is where interested leads get lost. Underfive sorts every reply and answers the ones that matter.

How does it work?

  1. 1

    Connect your sending tool

    An API key or OAuth connection. Replies from every mailbox start landing in one inbox.

  2. 2

    Every reply is categorised

    Interested, meeting request, question, out of office, not now, unsubscribe and more.

  3. 3

    Interested ones get booked

    An answer in your voice from the same mailbox, real times, and an invite.

How does it compare?

UnderfiveSequencer master inboxForward to a rep
Answers the reply Yes, in under 5 minutesNo, you doWhen the rep sees it
Same mailbox and thread YesYesOften not
Works across tools All in one inboxOne tool onlyEmail forwarding
Books the meeting YesNoManually
Follows up AutomaticallySequence onlyRarely

What you get with Underfive

Every major sequencer

Smartlead, Instantly, Email Bison, PlusVibe, Lemlist, Gmail and Outlook.

Deliverability-friendly

Replies go out in the existing thread from the original mailbox, never from a new domain.

No cap on mailboxes

Connect every sending inbox, including Azure and Outlook tenants.

Out-of-office aware

OOO replies are read and the follow-up waits until they are back.

Learn more Smartlead →Instantly →Email Bison →

Frequently asked questions

Which cold email tools does it work with?

Smartlead, Instantly, Email Bison, PlusVibe, Lemlist, Gmail and Outlook, with more added regularly.

Does it reply from my sending mailbox?

Yes. Each answer goes out from the mailbox the prospect replied to, in the same thread.

What happens with out-of-office replies?

They are categorised as out of office, and follow-ups wait until the prospect is back.

How many mailboxes can I connect?

There is no cap on mailboxes connected through your sending tools.

Can it handle pricing questions?

Yes, from your knowledge base. You can also require approval on pricing replies before they are sent.

More on AI appointment setting

Your next interested reply could be a booked meeting.